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Year Number of Results
1998 2
1999 1
2005 2
2010 1
2011 1
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2019 1
2020 1
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2022 1
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11 results

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Page 1
Ferroptosis, trophoblast lipotoxic damage, and adverse pregnancy outcome.
Beharier O, Kajiwara K, Sadovsky Y. Beharier O, et al. Placenta. 2021 May;108:32-38. doi: 10.1016/j.placenta.2021.03.007. Epub 2021 Mar 16. Placenta. 2021. PMID: 33812183 Free PMC article. Review.
This distinctive form of lipotoxic cell death has been recently implicated in multiple human diseases, spanning ischemia-reperfusion heart injury, brain damage, acute kidney injury, cancer, and asthma. Intriguingly, settings that have been associated with ferroptosis are l …
This distinctive form of lipotoxic cell death has been recently implicated in multiple human diseases, spanning ischemia-reperfusion heart i …
Comprehensive analysis of immune ferroptosis gene in renal clear cell carcinoma: prognosis and influence of tumor microenvironment.
Yang LH, Xu LZ, Huang ZJ, Pan HH, Wu M, Wu QY, Lu T, Zhang YP, Zhu YB, Wu JB, Luo JW, Yang GK, Ye LF. Yang LH, et al. Am J Transl Res. 2022 Sep 15;14(9):5982-6010. eCollection 2022. Am J Transl Res. 2022. PMID: 36247256 Free PMC article.
Subcellular fluorescence localization revealed that ACADSB, CHAC1, and PLA2G6 were distributed in the cytoplasm and LURAP1L in the nucleus. ...Single-cell RNA sequencing mapping revealed that ACADSB was enriched in distal tubule cell clusters. In the Kidney renal cl …
Subcellular fluorescence localization revealed that ACADSB, CHAC1, and PLA2G6 were distributed in the cytoplasm and LURAP1L in the nu …
Expression of PLA2G6 in human fetal development: Implications for infantile neuroaxonal dystrophy.
Polster B, Crosier M, Lindsay S, Hayflick S. Polster B, et al. Brain Res Bull. 2010 Nov 20;83(6):374-9. doi: 10.1016/j.brainresbull.2010.08.011. Epub 2010 Sep 9. Brain Res Bull. 2010. PMID: 20813170 Free PMC article.
Mutations in PLA2G6, which encodes calcium-independent phospholipase A(2) group VIA (iPLA2-VIA), underlie the autosomal recessive disorder infantile neuroaxonal dystrophy (INAD). ...In the eye, expression is seen in the lens and retina at all stages examined. PLA2G6 …
Mutations in PLA2G6, which encodes calcium-independent phospholipase A(2) group VIA (iPLA2-VIA), underlie the autosomal recessive dis …
Identification and distribution of endoplasmic reticulum iPLA2.
Kinsey GR, Cummings BS, Beckett CS, Saavedra G, Zhang W, McHowat J, Schnellmann RG. Kinsey GR, et al. Biochem Biophys Res Commun. 2005 Feb 4;327(1):287-93. doi: 10.1016/j.bbrc.2004.12.016. Biochem Biophys Res Commun. 2005. PMID: 15629460
ER-iPLA2 activity was observed in microsomes from rabbit and rat kidney, heart, and brain as well as in human kidney (Caki-1 and HEK293) and glioblastoma (A172) cell lines. ...Immunoblot analysis and PLA2 inhibitor studies with methyl arachidonyl fluorophosphonate a …
ER-iPLA2 activity was observed in microsomes from rabbit and rat kidney, heart, and brain as well as in human kidney (Caki-1 a …
Small-cell variant renal oncocytoma: Case report on its clinicopathological and genetic characteristics and literature review.
Li K, Wang C, Xiong X, Ma H, Qi Y, Hu W, Xiao S, Zhou X, Pang L, Zou H. Li K, et al. Gene. 2020 Mar 10;730:144266. doi: 10.1016/j.gene.2019.144266. Epub 2019 Dec 3. Gene. 2020. PMID: 31809837 Review.
Findings from the molecular genetic analysis of our case suggests that metabolic pathway-related genes (PIK3R5, PI3KCB, PLA2G4E, PLA2G2A, PLA2G6, PLCB4, PLCG2) may be exploited as potential targets for diagnosis and treatment when necessary. ...
Findings from the molecular genetic analysis of our case suggests that metabolic pathway-related genes (PIK3R5, PI3KCB, PLA2G4E, PLA2G2A, …
cDNA cloning and expression of a novel family of enzymes with calcium-independent phospholipase A2 and lysophospholipase activities.
Portilla D, Crew MD, Grant D, Serrero G, Bates LM, Dai G, Sasner M, Cheng J, Buonanno A. Portilla D, et al. J Am Soc Nephrol. 1998 Jul;9(7):1178-86. doi: 10.1681/ASN.V971178. J Am Soc Nephrol. 1998. PMID: 9644627
Their report describes the cloning of a full-length rat cDNA encoding CaIPLA2, using sequences derived from the purified rabbit kidney cortex enzyme. In addition, cDNA from rabbit kidney that encode the rabbit homologue of the enzyme and a closely related isoform we …
Their report describes the cloning of a full-length rat cDNA encoding CaIPLA2, using sequences derived from the purified rabbit kidney …
Cloning and expression of rat lung acidic Ca(2+)-independent PLA2 and its organ distribution.
Kim TS, Dodia C, Chen X, Hennigan BB, Jain M, Feinstein SI, Fisher AB. Kim TS, et al. Am J Physiol. 1998 May;274(5):L750-61. doi: 10.1152/ajplung.1998.274.5.L750. Am J Physiol. 1998. PMID: 9612290

Immunocytochemistry showed the presence of aiPLA2 in alveolar type II cells, alveolar macrophages, and bronchiolar epithelium. In the brain, heart, liver, kidney, spleen, and intestine, aiPLA2 mRNA content was < 50% of that in the lung, immunoreactive protein was not de

…
Immunocytochemistry showed the presence of aiPLA2 in alveolar type II cells, alveolar macrophages, and bronchiolar epithelium. In the brain, …
The effect of inhibition of Ca2+-independent phospholipase A2 on chemotherapeutic-induced death and phospholipid profiles in renal cells.
Zhang L, Peterson BL, Cummings BS. Zhang L, et al. Biochem Pharmacol. 2005 Nov 25;70(11):1697-706. doi: 10.1016/j.bcp.2005.09.008. Epub 2005 Oct 13. Biochem Pharmacol. 2005. PMID: 16226224
We demonstrate that cells derived from primary cultures of rabbit proximal tubules (RPTC), human embryonic kidney (HEK293) and human kidney carcinomas (Caki-1) express microsomal Ca(2+)-independent phospholipase A(2) (iPLA(2)gamma) and cytosolic Ca(2+)-independent p …
We demonstrate that cells derived from primary cultures of rabbit proximal tubules (RPTC), human embryonic kidney (HEK293) and human …
A novel mitofusin 2 mutation causes canine fetal-onset neuroaxonal dystrophy.
Fyfe JC, Al-Tamimi RA, Liu J, Schäffer AA, Agarwala R, Henthorn PS. Fyfe JC, et al. Neurogenetics. 2011 Aug;12(3):223-32. doi: 10.1007/s10048-011-0285-6. Epub 2011 Jun 4. Neurogenetics. 2011. PMID: 21643798 Free PMC article.
We recently reported autosomal recessive fetal-onset neuroaxonal dystrophy (FNAD) in a large family of dogs that is not caused by mutation in the PLA2G6 locus (Fyfe et al., J Comp Neurol 518:3771-3784, 2010). Here, we report a genome-wide linkage analysis using 333 microsa …
We recently reported autosomal recessive fetal-onset neuroaxonal dystrophy (FNAD) in a large family of dogs that is not caused by mutation i …
11 results